Growing global tech businesses
out of Bristol

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Helping you make your impact in the world

Our support is designed for you. If you join us, you’ll enjoy tailored support crafted around your ambitions and introductions to an amazing network of companies and advisers.

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Your success is our success

We’ve helped over 450 companies, in 20+ sectors, raise over £742 million in investment.

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Jack Fertility logo, black text with black swirl graphic

Lily and Nick at Jack Fertility - changing the game in male fertility testing

"SETsquared Bristol has played a key role in turning our idea into reality. The expert advice, practical workshops, personalised coaching and support has helped us to sharpen our business strategy, prepare for funding, and grow our reach."

Jack Fertility logo, black text with black swirl graphic

Andrew at Fathom - global leader in flood and climate risk

"SETsquared Bristol was invaluable in educating the founding team in how to structure and build a company. The mentoring was also very useful, and we made some great connections at events."

Ferryx logo, blue and oragne text with circles

Jenny at Ferryx - innovative biotech solutions to common gut problems

"SETsquared Bristol is helping me to learn and grow my business skills, constantly challenging me and keeping me on track, all within a thriving, supportive community of like-minded individuals."

Ferryx logo, blue and oragne text with circles

Neciah at FluoretiQ - revolutionising bacterial diagnostics

“It’s incredibly useful to meet entrepreneurs with similar challenges to share solutions. We have a much wider network through SETsquared, ensuring our developments can be heard by those who need to hear them ...”

Fast track your tech business

Hear from our companies on how SETsquared Bristol has helped them grow their businesses.

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Featured news and insights

A headshot of the SETsquared Bristol Centre Manager, Caroline Thompson

Is your tech business ready for an incubator?

2nd September 2025
Caroline Thompson, SETsquared Bristol Centre Manager, reflects on what we look for when selecting new technology startups, and the questions to ask yourself before you apply to the incubator.   SETsquared Bristol has...
Three women sitting on chairs speaking at a panel event called Startup Stories: Spinout Edition

Startup Stories – Spinout Edition

28th July 2025
The latest panel event in the Startup Stories series, Spinout Edition, saw two University of Bristol spinout leaders share their journeys—from academic labs to building businesses to short funding runways...
University of Bristol - New Enterprise Awards Evening, Engine Shed

Deeptech graduate startups win membership to SETsquared Bristol 

26th June 2025
Two deeptech graduate startups from the University of Bristol are joining our SETsquared Bristol Propel incubation programme.  Fidelis AI and EarTide are prize winners of the New Enterprise Competition, the University of Bristol’s...
More news and insights